EDM, first, I am not related to the website I am going to talk about at all, but my personal league has been using Fanball Commissioner (
http://www.fanball.com/) for the last 4 or 5 years. I will admit, every year, the beginning of the season is a little rough, they offer the first couple weeks free as a trial. But it's mostly only an issue for those players that sit in front of their PC wanting instant stats. If you are the type to check in a handfull of times on Sunday, knowing it is going to be a bit busy, you will be fine. After those first couple weeks, I have not had any problems.
Commissioner gives you the option of configuring your league the way that you want. Ours is one division of eight teams. I am pretty sure I have seen two divisions with 16 team leagues. At $60 bucks for the year, I think it is worth it. Much better than Yahoo (free) or CBS ($120).
Just thought I would share it with you. If you are needing an owner to make things even, I might be interested. But as comissioner of another league, owner of a team in that league, and RAMS fan, I am not sure I would do it otherwise. But good luck!